The guide Namorat linked is good.
Anyway, a great team you may use (from the first run to O+2) is: Zem/Tholin(use Zem if you meet many Arachna); Serafine; Taurus; Xanos; Jasmine.
Tholin, Xanos, Taurus and Jasmine can interrupt channeling, Cara, etc.
Remember to charge your own Cara's ult to face Ezio.
15/15 since day 2 in CoF, both runs(when swipe was not possible) with that comp
If you don't have Xanos or Serafine, Gizmo is good
EDIT: obviosuly, before Zem I used to use Tholin; before Taurus I used to use Gizmo, as I suggested.
Against Vincent/Namtar frontline; use Bloodspear, Garrick or Gale.
All these heroes are pretty easy to acquire since low level, that's why I suggest them.
If you well time your ults, you can complete your CoF in about 10 minutes, including loading
EDIT 2: as Namorat suggested, Riley is a really strong hero for CoF until Orange fusion; then she's pretty weak.
Namorat's teams are really strong aswell. I suggest you to test all these teams(based on your heroes) to find the one you feel better with